How do I uncheck grayscale printing in my Mac OS X? To deactivate grayscale printing in your Mac OS X, open the Print dialog box by clicking on File and then selecting 'Print' from inside the application being printed from. Select 'Quality & Media' from the pop-up menu. Click the 'Grayscale Printing' check box to remove the checkmark. Finally, Click 'Print'. Printing will now begin.